Wilke is the author of approximately scientific papers. In , Dr.
Molecular Genetics of Natural Populations | Molecular Biology and Evolution | Oxford Academic
Abstract Much molecular-evolution research is concerned with sequence analysis. Introduction The field of molecular evolution investigates how genes and genomes evolve over time. Identifying Fundamental Principles of Molecular Evolution Besides understanding and interpreting specific evolutionary events, evolutionary biologists also aim to identify fundamental principles of molecular evolution. Predicting Probable Evolutionary Trajectories For many real-world applications, it would be useful to be able to predict future evolutionary events.
Summary There is a growing trend in widely differing subfields of molecular evolution to increase biophysical realism in computational models of sequence evolution. Author's Biography Claus O. References 1. View Article Google Scholar 2. View Article Google Scholar 3. Mol Biol Evol — View Article Google Scholar 4.
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Scientists develop new theory of molecular evolution
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Previous Article. Gene expression profiling using whole genome microarray with 4, open reading frames revealed over-representation of the transport functional category in all evolved lines. Excess nutrient adapted lines were found to exhibit greater degrees of positive correlation, indicating parallelism between ancestor and evolved lines, when compared with prolonged stationary phase adapted lines. Gene-metabolite correlation network analysis revealed over-representation of membrane-associated functional categories. Proteome analysis revealed the major role played by outer membrane proteins in adaptive evolution.
In summary, we report the vital involvement of energy metabolism and membrane-associated functional categories in all of the evolutionary conditions examined in this study within the context of transcript, outer membrane protein, and metabolite levels. These initial data obtained may help to enhance our understanding of the evolutionary process from a systems biology perspective. Most micro-organisms grow in environments that are not favorable for their growth.
The level of nutrients available to them is rarely optimal.